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Schistosoma mansoni
Diseases | Sites and Sources | Diagnostic Factors | Virulence Factors | Treatment and Prevention | Commentary
- Category
- blood fluke
- Classification
- helminth, trematode
Schistosomiasis mansoni (Bilharziasis)
| fever |
eosinophilia |
abdominal pain |
| diarrhea, bloody |
diarrhea, inflammatory |
blood in stool |
| fecal leukocytes |
lymphadenopathy |
splenomegaly |
| ascites |
dermatitis |
cough |
| esophageal varices |
hepatic portal fibrosis |
portal hypertension |
| hepatomegaly |
hypertension |
transverse myelitis |
| encephalopathy |
CNS damage |
|
Schistosomal dermatitis (Swimmer's itch)
| itching |
inflammation |
|
| subtropics, source |
tropics, source |
fresh water, source |
| snails, source |
African rivers, source |
Carribean rivers, source |
| South American rivers, source |
lung, pathogen |
skin, pathogen |
| CNS, pathogen |
GI tract, pathogen |
mesenteric veins, pathogen |
| inferior mesenteric veins, pathogen |
blood, pathogen |
liver, pathogen |
| sanitation |
vector control |
praziquantel |
Schistosomiasis is an infection of high prevalence and morbidity. Three species of schistosomes cause human disease .These differ in geographic distribution (S. JAPONICUM, S. MANSONI, S. HAEMATOBIUM). Species also differ in location within the venous system but in all species, disease is produced primarily by acute and chronic inflammatory responses to schistosome eggs. Fibro-obstructive disease in the liver and portal hypertension are major responses to S. mansoni infections although there may be little or no overt disease with chronic infection. Transmission cycle is complex with a snail intermediate host. Swimmer's itch, which is caused by Schistosoma mansoni, can also be caused by other species of Schistosomes from birds or other animals.
Updated: May 12, 1999
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