Functional genomics - genetics regulatory networks
Dr. Baker’s research focus is in developing gene expression classifiers that can be used to diagnosis
illness, predict clinical course and ultimately responsiveness to therapy. Dr. Baker is a participating
investigator in Large Scale Collaborative Research Program Inflammation and the Host Response
(U54 GM-62118). His laboratory serves as one of three genomic cores for this program. The others
are Washington University School of Medicine and the Genomics Center at Stanford University.
He is a member of the computational analysis and modeling core of the program. The main goals
of this project are using microarrays to determine whether patterns of gene expression from
whole blood leukocytes can be used to identify trauma and burned patients at risk of developing MODS.
The Baker lab is also dedicated to assisting other researchers interested in applying the tools of functional genomics including microarray technology and bioinformatics to medically important problems.
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