Bacterial Genetics and Physiology    GMS 6038
Fall 2008 (in progress)
 9:35-10:25 a.m.; R2-265
Paul A. Gulig, Ph.D.
 gulig@ufl.edu

Syllabus

Text: Molecular Genetics of Bacteria, Third Edition (Second Edition will also do), Snyder and Champness, ASM Press (available in the Health Science Center Bookstore)

Online Escherichia coli and Salmonella typhimurium (connection via UF network required)

Send me an introductory email
 
Dates Subject Handouts Text Reading EcoSal Online Other
Aug. 24-31 Introduction - Refresher on bacterial structure and physiology, antibiotics and resistance

X

 Introduction Structure-function of the cell; Outer Membrane; Peptidoglycan; Cytoplasmic Membrane; Flagella and Motility; LPS Growth rate,
Beta-lactams and vancomycin
Sept. 5 Expression: Transcription and translation

X

 Chapter 2 Transcription; Translation  
Sept. 5, 7 Protein secretion

X

 Chapters 2, 14 Sec-dependent;  Across outer membrane Type VI commentary
Sept. 10 DNA replication

X

 Chapter 1 Initiation of chromosome replication; Replication fork added to handout
Sept. 12-14 Plasmid genetics and biology

X

 Chapter 4 Plasmid replication Study Guide, pCVD442
Sept. 17-19 Bacteriophages

X

 Chapters 7 and 8   Lambda Guide,
Phage display
Sept. 21-23 Paradigms of transcriptional regulation
 

X

 Chapter 12    
Sept. 26 Global regulation

X

 Chapter 13    
xx Final Exam xx        

ASSIGNMENTS
Homework on Growth Rate; Key; Due xx
 Homework on Protein Export and Secretion; Key; Due xx
 Extra credit homework on Expression; Key; Due xx
 Homework on Plasmids; Key; Due xx
 Homework on Regulation of Expression; Key

Old Exams (may not necessarily match style for 2007)
2007 - Exam - Key
2006 - Exam - Key
 2005 - Exam - Key (this was a closed book in class exam, followed by an oral exam on the unanswered questions)
2004 - Exam - Key
2003 - Exam - Key
2002 - Exam
2001 - Exam - Key
2000 - Exam - Key
1999 - Exam - Key