Immunology/Microbiology Journal Club
GMS6921
Fall 2007
Thursday, 12:00-1:00
R2-265
Director: Dr. L.J. Chang (lchang@mgm.ufl.edu)

Recommended articles (feel free to recommend one to Dr. Chang)


If you choose an article not on this list, please consult with Dr. Chang at least one week in advance.  Please keep in mind that the article should represent a whole new and exciting discovery - a paradigm shift in our understanding of immunity and/or microbiology - preferably a combination of the two fields - NOT an incremental addition to an ongoing story.  It should not be so focused in its scope that only a few members of the journal club will find it interesting.

Schedules from previous years with links to papers presented: 2004; 2005; 2006

Tips on preparing and delivering a good presentation.

Link to Anonymous Presentation Evaluation

University of Florida - EZProxy to Remotely Access Online Resources

Schedule

Please arrive 5 minutes early to get your food and drink.

Date Presenter Critique* Article
8/23     Organizational Meeting
8/30 Pui Lee Sushrusha Nayak Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells.Science. 2007 Mar 9;315(5817):1398-401. Supplemental material; Comment in: Science. 2007 Mar 9;315(5817):1376-7.
9/6 Matthew Parker Matthew Delano Bettelli E, Carrier Y, Gao W, Korn T, Strom TB, Oukka M, Weiner HL, Kuchroo VK.  Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells.  Nature. 2006 May 11;441(7090):235-8. Epub 2006 Apr 30.
9/13
R5-265
Roslyn Frank Erika Eksioglu

Noam Stern-Ginossar et al.  Host Immune System Gene Targeting by a Viral miRNA. Science 317, 376 (2007); supporting online material

9/20 Jason Weinstein Wilton Williams "Monitoring of blood vessels and tissues by a population of monocytes with patrolling behavior"  (Science 317:666-670, 2007); supporting online material
9/27 Jeanette Lo-Dauer Ekta Patel Shen-Ying Zhang, Emmanuelle Jouanguy, Sophie Ugolini, et al. TLR3 Deficiency in Patients with Herpes Simplex Encephalitis.  Science Vol. 317. no. 5844, pp. 1522 - 1527
10/4 Joshua Bunger Amanda Barrett Randall G, Panis M, Cooper JD, Tellinghuisen TL, Sukhodolets KE, Pfeffer S, Landthaler M, Landgraf P, Kan S, Lindenbach BD, et al. Cellular cofactors affecting hepatitis C virus infection and replication. (2007)  Proc Natl Acad Sci USA 104:12884-12889.
10/11 Cynthia Wang Kaleb Pauley

Georgantas RW 3rd, Hildreth R, Morisot S, Alder J, Liu CG, Heimfeld S, Calin GA, Croce CM, Civin CI. CD34+ hematopoietic stem-progenitor cell microRNA expression and function: a circuit diagram of differentiation control.  Proc Natl Acad Sci U S A. 2007 Feb 20;104(8):2750-5. Epub 2007 Feb 9.

10/18 Amber Shatzer Starlyn Okada Malathi K, Dong B, Gale M, Silverman RH.  Small self-RNA generated by RNase L amplifies antiviral innate immunity.  Nature 2007 Aug 16 448(7155):816-9
10/25 Jennifer Joseph Sara Palmer Pathak SK, Basu S, Basu KK, Banerjee A, Pathak S, Bhattacharyya A, Kaisho T, Kundu M, Basu J. Direct extracellular interaction between the early secreted antigen ESAT-6 of Mycobacterium tuberculosis and TLR2 inhibits TLR signaling in macrophages. Nat Immunol. 2007 Jun;8(6):610-8.
11/1 Carla Cuda Maxim Salganik Nature Immunology 8[11]:1246-1254; Upregulation of CTLA-4 by HIV-specific CD4(+) T cells correlates with disease progression and defines a reversible immune dysfunction. Kaufmann DE, et al.
Review related to the above paper: Immunity, Vol 27, 406-416, 21 September 2007. Review. Human Immunodeficiency Virus Controllers: Mechanisms of Durable Virus Control in the Absence of Antiretroviral Therapy.  SG. Deeks and BD. Walker
11/8 Tolga Barker Sarah Guilmain “Conversion of mature B cells into T cells by dedifferentiation to uncommitted progenitors” (Nature 449:473-477, 2007)
11/15 Aparna Manoharan Jennifer Bess "Interferon modulation of cellular microRNAs as an antiviral mechanism"  (Nature 449:919-922, 18 October 2007) Irene M. Pedersen, Guofeng Cheng, Stefan Wieland, Stefano Volinia, Carlo M. Croce, Francis V. Chisari & Michael David; Supplemental material
11/22 Thanksgiving Holiday    
11/29 Dacia Kwiatkowski Daniel Perry "Plasmodium circumsporozoite protein promotes the development of the liver stages of the parasite"  (Cell 131:492–504, 2007)
12/6 11:00-1:00 First Year Students   Reports from First Lab Rotations.  
Pizza will be provided.

*We instituted a new policy this year after the organizational meeting.  We paired a younger student with the senior presenting student to critique the presentation and PowerPoint BEFORE the journal club.  Link to online form for the critique before the presentation.  The critique should be submitted no later than the day before the journal club.